cell receptor tcr therapy closeup view illustration |
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navigate by keyword : car cell chimeric antigen receptor tcr dendritic targeted biological therapy immunotherapy lymphocytic leukemia chemotherapy multiple myeloma neutrophil lymphoblastic acute myeloid non hodgkin lymphoma leukaemia amyloid chronic myelogenous malignant growths mds metastasis dna erythrocytes anemia biopsy blood antibody stem basophil bone marrow cancer dutcher bodies lymphocyte hypergranular promyelocytic oncology treatment monocyte tumor view isometric closeup |
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T cell receptor T cell therapy (TCR-T) is a type of adoptive T-cell therapy that targets some cancers. TCR-T therapies use heterodimers made of alpha and beta peptide chains to recognize MHC-presented polypeptide fragment molecules. Unlike CAR-T, which uses cell surface antigens, TCR-T can recognize MHC's larger set of intracellular antigen fragments. However, TCR-T cell therapy depends on MHC molecules, limiting its usefulness. |
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