the gastric proton pump atpase with inhibitor ppi bound |
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navigate by keyword : acid acidrelated atpase blocker cell competitive disease diseases drug dudodenal enzyme gastric inhibition inhibitor juice lipid medical membrane omeprazole parietal pharmacology potassiumcompetitive ppi protein proton pump reflux stomach ulcer vonoprazan |
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The gastric proton pump acidifies the gastric juice down to pH 1. It is a target for drugs that treat acid-related diseases including gastroesophageal reflux disease GERD and gastric and duodenal ulcers. Source: PDB entry 5yIu |
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